Brevianamides with antitubercular potential from a marine-derived isolate of Aspergillus versicolor.
نویسندگان
چکیده
An Aspergillus versicolor isolated from sediment collected from the Bohai Sea, China, yielded the new dimeric diketopiperazine brevianamide S (1), together with three new monomeric cometabolites, brevianamides T (2), U (3), and V (4). Structures were determined by detailed spectroscopic analysis. Brevianamide S exhibited selective antibacterial activity against Bacille Calmette-Guérin (BCG), suggestive of a new mechanism of action that could inform the development of next-generation antitubercular drugs.
منابع مشابه
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عنوان ژورنال:
- Organic letters
دوره 14 18 شماره
صفحات -
تاریخ انتشار 2012